Last update :
21/02/2024
References   References 575  
Type : Journal

Research teams : Boston - Brigham and women\'s hospital
Authors : Holmes CJ, Ausman RK, Kundsin RB, Walter CW.
Title : Effect of freezing and microwave thawing on the stability of six antibiotic admixtures in plastic bags.
Reference : Am J Hosp Pharm ; 39: 104-108. 1982

Level of Evidence : 
Biological analysis
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
No comments for the degradation products

List of drugs
InjectionAmikacin sulfate Antibiotic
Stability in solutions Polyvinyl chloride Glucose 5% 20 mg/ml -20°C Protect from light
30 Day
InjectionAmpicillin sodium Antibiotic
Factors which affect stability Temperature -20°C Induces Degradation
InjectionClindamycin phosphate Antibiotic
Stability in solutions Polyvinyl chloride Glucose 5% 6 mg/ml -20°C Protect from light
30 Day
InjectionNafcillin sodium Antibiotic
Stability in solutions Polyvinyl chloride Glucose 5% 20 mg/ml -20°C Protect from light
30 Day
InjectionTobramycin sulfate Antibiotic
Stability in solutions Polyvinyl chloride Glucose 5% 3,2 mg/ml -20°C Protect from light
30 Day

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