Last update :
12/12/2025
References   References 5096  
Type : Journal
Web link : https://doi.org/10.1016/j.curtheres.2025.100810

Research teams : Shanxi - Second hospital of Shanxi Medical University CN, Taiyuan, Shanxi, China
Authors : Zhang L, Kong L, Deng Q, Chao Y, Fu C, Meng Y.
Title : Compatibility and Stability of Cipepofol (Ciprofol) and Etomidate Mixture for Intravenous Anesthesia.
Reference : Current Ther Res ; 103: 100810. 2025

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
No comments for the degradation products

List of drugs
injectionCipepofol General anesthetic
Compatible 0,2 mg/ml + injectionEtomidate 1 mg/ml + None
injectionEtomidate General anesthetic
Compatible 1 mg/ml + injectionCipepofol 0,2 mg/ml + None
Stability of mixtures
Not specified None 25°C Not specified
injection Cipepofol 0,2 mg/ml
injection Etomidate 1 mg/ml
24 Hour
Not specified None 37°C Not specified
injection Cipepofol 0,2 mg/ml
injection Etomidate 1 mg/ml
24 Hour
Not specified None 4°C Not specified
injection Cipepofol 0,2 mg/ml
injection Etomidate 1 mg/ml
24 Hour

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