| Type : |
Journal |
| Web link : |
https://ijpc.com/Abstracts/Abstract.cfm?ABS=5473 |
|
| Research teams : |
Houston - Professional Compounding Centers of America (PCCA) |
| Authors : |
Davis C, Ip K, Banov D, Zdoryk O. |
| Title : |
Stability Study of Pediatric Oral Suspensions Formulated with PCCA SuspendIt Vehicle Used for the Treatment of Cardiovascular Disease. |
| Reference : |
Int J Pharm Compound ; 29, 4: 279-290. 2025 |
|
| Level of Evidence : |
|
| Physical stability : |
|
| Chemical stability : |
|
| Other methods : |
|
| Comments : |
|
List of drugs
 Captopril
|
 |
 |
 |
 |
100 mg
® = ? |
| Ascorbic acid |
500 mg |
| Citric acid |
900 mg |
| Suspendit® |
>> 100 ml |
|
2-8°C |
 |
| 180 |
 |
|
|
|
|
|
500 mg
® = ? |
| Ascorbic acid |
500 mg |
| Citric acid |
900 mg |
| Suspendit® |
>> 100 ml |
|
2-8°C |
|
| 180 |
|
|
|
|
|
Metoprolol tartrate
|
 |
|
|
|
100 mg
® = ? |
| Citric acid |
500 mg |
| Citric acid |
1% >> pH 3.6-4.6 |
| NaOH |
1% >> pH 3.6-4.6 |
| Suspendit® |
>> 100 ml |
|
20-25°C |
|
| 180 |
|
|
|
|
|
|
1000 mg
® = ? |
| Citric acid |
500 mg |
| Citric acid |
1% >> pH 3.6-4.6 |
| NaOH |
1% >> pH 3.6-4.6 |
| Suspendit® |
>> 100 ml |
|
20-25°C |
|
| 180 |
|
|
|
|
|
