Last update :
05/12/2025
References   References 4944  
Type : Journal
Web link : https://doi.org/10.1093/jacamr/dlaf074

Research teams : Brisbane - The University of Queensland Centre for Clinical Research, Brisbane, Queensland, Australia
Authors : Wolie Z.T, Unwin S, Burke A, Won H, Wallis S.C, Seaton R.A, Gilchrist M, Roberts J.A, Sime F.B.
Title : Evaluation of the stability of tigecycline in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy.
Reference : JAC Antimicrob Resist ; 7, 3 2025

Level of Evidence : 
Level of evidence A+
Physical stability : 
Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionTigecycline Antibiotic
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 0,2 >>0,83 mg/ml 2-8°C Not specified
7 Day
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 0,2 >>0,83 mg/ml 32°C Not specified
24 Hour

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