Last update :
16/07/2025
References   References 4935  
Type : Journal
Web link : https://doi.org/10.3344/kjp.24316

Research teams : Séoul - Department of Anesthesiology and Pain Medicine, Korea University Medical Center, Guro Hospital, Seoul , Republic of Korea.
Authors : Lee C.H.
Title : Physicochemical stability of mixtures of nonsteroidal anti-inflammatory drugs such as ketorolac and diclofenac and antiemetics such as ondansetron and ramosetron: an in vitro study.
Reference : Korean J Pain 2025;38(2):103-115. 2025

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionDiclofenac Anti-inflammatory
Incompatible 18,75 mg/ml + injectionOndansetron hydrochloride 1,25 mg/ml + Sodium chloride 0,9%
Compatible 18,75 mg/ml + injectionRamosetron hydrochloride 0,075 µg/ml + Sodium chloride 0,9%
injectionKetorolac tromethamine Anti-inflammatory
Incompatible 15 mg/ml + injectionOndansetron hydrochloride 1,25 mg/ml + Sodium chloride 0,9%
Compatible 15 mg/ml + injectionRamosetron hydrochloride 0,075 µg/ml + Sodium chloride 0,9%
injectionOndansetron hydrochloride Antiemetic
Incompatible 1,25 mg/ml + injectionDiclofenac 18,75 mg/ml + Sodium chloride 0,9%
Incompatible 1,25 mg/ml + injectionKetorolac tromethamine 15 mg/ml + Sodium chloride 0,9%
injectionRamosetron hydrochloride Antiemetic
Compatible 0,075 µg/ml + injectionDiclofenac 18,75 mg/ml + Sodium chloride 0,9%
Compatible 0,075 µg/ml + injectionKetorolac tromethamine 15 mg/ml + Sodium chloride 0,9%

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