Last update :
05/12/2025
References   References 4927  
Type : Poster
Icone.pdf
346Ko

Research teams : Paris - Hôpital Robert Debré, Service pharmacie
Authors : Jegaden S, Boucida M, Alloh D, Claraz P, Roupret-Serzec J, Storme T, Rioblanc F.
Title : Préparation d'étoposide injectable concentrée à 10 mg/mL : intérêts et stabilité physicochimique.
Reference : GERPAC Congress 2024

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Unencrypted results (eg graphic)

List of drugs
injectionEtoposide Anticancer drug
Factors which affect stability Temperature 4°C10 mg / ml Induces Precipitation
Stability in solutions Polyolefine Sodium chloride 0,9% 10 mg/ml 20-25°C Not specified
7 Day

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