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16/07/2025
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References 4921
Type :
Journal
Web link :
https://ijpc.com/Abstracts/Abstract.cfm?ABS=5431
Research teams :
Rotterdam - Fagron BV
Authors :
Schettino C, Marianni B, Polonini H.
Title :
Compatibility of 17-a-estradiol, Caffeine, Clobetasol Propionate, Finasteride, Melatonin, Metronidazole, Spironolactone, Tretinoin, and Triamcinolone in Trichosol, a Natural Vehicle for Hair Solutions.
Reference :
Int J Pharm Compound ;29,1:64-76 2025
Level of Evidence :
Physical stability :
Chemical stability :
Other methods :
Comments :
List of drugs
Caffeine
100 mg
® = ?
TrichoSol®
>> 100 ml
23-27°C
180
2000 mg
® = ?
TrichoSol®
>> 100 ml
23-27°C
180
Clobetasol propiomate
10 mg
® = ?
Transcutol®
6 g
TrichoSol®
>> 100 ml
23-27°C
90
100 mg
® = ?
Transcutol®
6 g
TrichoSol®
>> 100 ml
23-27°C
90
Estradiol
25 mg
® = ?
polysorbate 20
2,5 g
TrichoSol®
>> 100 ml
23-27°C
180
50 mg
® = ?
polysorbate 20
2,5 g
TrichoSol®
>> 100 ml
23-27°C
180
Finasteride
250 mg
® = ?
oleic acid
2 g
Cremophor RH 40
5 g
TrichoSol®
>> 100 ml
25°C
60
10 mg
® = ?
oleic acid
2 g
Cremophor RH 40
5 g
TrichoSol®
>> 100 ml
25°C
60
Melatonine
50 mg
® = ?
TrichoSol®
> 100 ml
25°C
60
500 mg
® = ?
TrichoSol®
> 100 ml
25°C
60
Metronidazole
750 mg
® = ?
TrichoSol®
> 10 ml
25°C
180
Spironolactone
1 g
® = ?
Cremophor RH 40
6 g
TrichoSol®
>> 100 ml
25°C
120
Tretinoin
10 mg
® = ?
oleic acid
3 g
Cremophor RH 40
5 g
NaOH
50% > pH 4.0
25°C
60
100 mg
® = ?
oleic acid
3 g
Cremophor RH 40
5 g
NaOH
50% > pH 4.0
25°C
60
Triamcinolone acetonide
50 mg
® = ?
oleic acid
2 g
NaOH
50% > pH 3.5
polysorbate 80
5 g
TrichoSol®
>> 100 ml
25°C
180
100 mg
® = ?
oleic acid
2 g
NaOH
50% > pH 3.5
polysorbate 80
5 g
TrichoSol®
>> 100 ml
25°C
180
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