Last update :
03/05/2024
References   References 489  
Type : Journal

Research teams : Barcelona - Universitat de Barcelona, Facultat de farmacia
Authors : Munoz M, Girona V, Pujol M, Duran S, Vicente P, Solé LA.
Title : Stability of ifosfamide in 0.9% sodium chloride solution or water for injection in a portable IV pump cassette.
Reference : Am J Hosp Pharm ; 49: 1137-1139. 1992

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
Comments : 
No comments for the degradation products
No visual inspection

List of drugs
InjectionIfosfamide Anticancer drug
Stability in solutions Polyvinyl chloride Water for Injection 80 mg/ml 35°C Not specified
8 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 10 mg/ml 25°C With or without light
8 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 10 mg/ml 4°C Protect from light
8 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 20 & 40 & 80 mg/ml 35°C Not specified
8 Day

  Mentions Légales