Last update :
08/12/2024
References   References 4825  
Type : Journal
Web link : https://doi.org/10.1016/j.farma.2024.01.007.

Research teams : Sevilla - University Hospital “Virgen del Rocío, Department of Pharmacy
Authors : Merino-Bohórquez V, Berisa-Prado S, Delgado-Valverde M, Tirado-Pérez M.J, García-Palomo M et al.
Title : Physicochemical and microbiological stability study of two new preservative-free methylprednisolone eye drops.
Reference : Farm Hosp 2024

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Eye-dropsMethylprednisolone sodium succinate Various
Factors which affect stability Temperature 25°C Induces Reduced stability
Factors which affect stability Concentration Reduced concentration Induces Reduced stability
Stability in solutions plastic bottle Medicine bottle for injection 50 mg
Solu-maderin®
Water for injection 1 mL
NaCl 0.9% >> 5 mL
2-8°C Protect from light
42 Day
Stability in solutions plastic bottle Medicine bottle for injection 5 mg
Urbason®
Water for injection 1,25 mL
NaCl 0.9% >> 5 mL
2-8°C Protect from light
21 Day

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