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References   References 4769  
Type : Journal

Research teams : Lille - Faculté des Sciences Pharmaceutiques et Biologiques
Authors : Roche M, Danel C, Simon N, Kouach M, Bouchfaa M, Berneron C, Odou P, Lannoy D.
Title : Cisatracurium Besylate 10 mg/mL Solution Compounded in a Hospital Pharmacy to Prevent Drug Shortages : A Stability Study Involving Four Degradation Products.
Reference : Pharmaceutics ;15,1404 2023

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
High Performance Liquid Chromatography - mass spectrometry (HPLC-MS)
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
Degradation products identified and quantified

List of drugs
InjectionCisatracurium besylate Curarimimetic
Stability in solutions Glass None 10 mg/ml 2-8°C Protect from light
450 Day

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