| Type : |
Journal |
| Web link : |
https://doi.org/10.1136/ejhpharm-2020-002597 |
|
| Research teams : |
Mainz - University Medical Center, Johannes Gutenberg |
| Authors : |
Knoll L, Kraemer I, Thiesen J. |
| Title : |
Physicochemical stability of carmustine-containing medicinal products after reconstitution and after dilution to ready-to-administer infusion solutions stored refrigerated or at room temperature |
| Reference : |
EJHP ; 30, 1: 11-16. 2023 |
|
| Level of Evidence : |
|
| Physical stability : |
|
| Chemical stability : |
|
| Other methods : |
|
| Comments : |
| Stability indicating capability inadequately assessed | | Method not shown but the article refers to a validated method | | Degradation products not observed in real conditions |
|
List of drugs
 Carmustine
|
 |
 |
 |
 |
3,3 mg/ml |
2-8°C |
 |
| 24 |
 |
|
|
|
 |
 |
0,2 mg/ml |
2-8°C |
|
| 48 |
|
|
|
|
|
|
0,2 mg/ml |
22°C |
|
| 6 |
|
|
|
|
|
|
1 mg/ml |
2-8°C |
|
| 48 |
|
|
|
|
|
|
1 mg/ml |
22°C |
|
| 8.5 |
|
|
|
|
|
