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References   References 4736  
Type : Journal
Web link : https://doi.org/10.1016/j.jpba.2023.115290
Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Closset M, Colsoul ML, Goderniaux N, Bihin B, Jamart J, Onorati S, Soumoy L, Hecq JD, Odou P, Galanti L.
Title : An Ultra-High-Performance Chromatography method to study the long term stability of gemcitabine in dose banding conditions.
Reference : J Pharm Biomed Anal 2023
Level of Evidence : 
Level of evidence B+
Physical stability : 
Visual examination Turbidimetry Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
InjectionGemcitabine hydrochloride Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 5,5>>6,6 mg/ml 2-8°C Not specified
49 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 5,5>>6,6 mg/ml 21-25°C Not specified
49 Day
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