Last update :
08/02/2023
References   References 4710  
Type : Poster
Icone.pdf
377Ko

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : D'Huart E, Sacrez M, Sobalak N, Vigneron J, Demoré B.
Title : Etude de stabilité physico-chimique du Cabazitaxel Zentiva® en flacons après "ouverture" et en solutions diluées en poches en perfusion de 3 types.
Reference : GERPAC Congrès - octobre 2022 2022

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionCabazitaxel Anticancer drug
Stability in solutions Polypropylene NaCl 0,9% or Glucose 5% 0,1 >>0,26 mg/ml 2-8°C Protect from light
28 Day
Stability in solutions Polyethylene NaCl 0,9% or Glucose 5% 0,1 >>0,26 mg/ml 25°C Protect from light
28 Day
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,1 >>0,26 mg/ml 25°C Protect from light
28 Day
Stability in solutions Partially used vials None 20 mg/ml 25°C Protect from light
28 Day

  Mentions Légales