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References   References 4472  
Type : Journal
Web link : https://www.mdpi.com/1999-4923/12/8/781
Research teams : Clermont-Ferrand - University Hospital Gabriel Monpied, Department of Pharmacy
Authors : Berton B, Chennell P, Yessaad M, Bouattour Y, Jouannet M, Wasiak M, Sautou V.
Title : Stability of Ophthalmic Atropine Solutions for Child Myopia Control.
Reference : Pharmaceutics ;12, 781 2020
Level of Evidence : 
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
List of drugs
Eye-dropsAtropine sulfate Antimuscarinic
Stability in solutions Plastic bottle Powder 0,6 mg
NaH2PO4 46,8 mg
Na2HPO4 26,88 mg
Cetrimide 0,6 mg
NaCl 0.9% >> 6 mL
23-27°C Protect from light
180 Day
Stability in solutions Plastic bottle Powder 0,6 mg
NaH2PO4 46,8 mg
Na2HPO4 26,88 mg
NaCl 0.9% >> 6 mL
23-27°C Protect from light
180 Day
  Mentions Légales