Last update :
04/08/2021
References   References 4460  
Type : Journal
Web link : https://doi.org/10.1038/s41598-019-42854-y

Research teams : Vienna - University of Vienna, Department of Pharmacognosy
Authors : Kussmann M, Ferth A, Obermüller M, Pichler P, Zeitlinger M, Wiesholzer , Burgmann H, Poeppl W, Reznicek G.
Title : Compatibility of ciprofloxacin with commercial peritoneal dialysis solutions.
Reference : Scientific reports 9:6512 2019

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values

List of drugs
InjectionCiprofloxacin lactate Antibiotic
Stability in solutions Polyvinyl chloride Extraneal® (Baxter) 47,6 mg/ml 25°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride Extraneal® (Baxter) 47,6 mg/ml 37°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Extraneal® (Baxter) 47,6 mg/ml 6°C Protect from light
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Stability in solutions Polyvinyl chloride Nutrineal® 47,6 mg/ml 25°C Protect from light
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Stability in solutions Polyvinyl chloride Nutrineal® 47,6 mg/ml 37°C Protect from light
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Stability in solutions Polyvinyl chloride Nutrineal® 47,6 mg/ml 6°C Protect from light
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Stability in solutions Polyvinyl chloride Physionéal® 1.36 (Baxter) 47,6 mg/ml 37°C Protect from light
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Stability in solutions Polyvinyl chloride Physionéal® 1.36 (Baxter) 47,6 mg/ml 6°C Protect from light
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Stability in solutions Polyvinyl chloride Physionéal® 2.27 (Baxter) 47,6 mg/ml 25°C Protect from light
48 Hour
Stability in solutions Polyvinyl chloride Physionéal® 2.27 (Baxter) 47,6 mg/ml 37°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Physionéal® 2.27 (Baxter) 47,6 mg/ml 6°C Protect from light
14 Day
Stability in solutions Polyvinyl chloride Physionéal® 3.86 (Baxter) 47,6 mg/ml 25°C Protect from light
48 Hour
Stability in solutions Polyvinyl chloride Physionéal® 3.86 (Baxter) 47,6 mg/ml 37°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Physionéal® 3.86 (Baxter) 47,6 mg/ml 6°C Protect from light
14 Day

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