Last update :
30/09/2020
References   References 4453  
Type : Poster
Icone.pdf
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Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Polo C, Vigneron J, D’Huart E, Charmillon A , Demoré B.
Title : Étude de stabilité physico-chimique d’une solution de cloxacilline à 250 mg/mL en seringues polypropylène et à 50-100 mg/mL en diffuseurs portables.
Reference : Synprefh Congress (Hopipharm), 2020. 2020

Level of Evidence : 
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionCloxacillin sodium Antibiotic
Factors which affect stability Temperature 37°CSodium chloride 0,9% Induces Precipitation
Factors which affect stability Temperature 37°CGlucose 5% Induces Precipitation
Stability in solutions Polypropylen Syringe Water for Injection 250 mg/ml 25°C Light
24 Hour

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