Last update :
30/09/2020
References   References 4431  
Type : Journal
Web link : http://dx.doi.org/10.1097/MD.0000000000013698

Research teams : Wuhan - Wuhan University, College of Pharmacy
Authors : Chen P, Chen F, Zhou B-H.
Title : Compatibility and stability of dezocine and tropisetron in 0.9% sodium chloride injection for patient-controlled analgesia administration.
Reference : Medicine ; 97:50(e13698) 2018

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed

List of drugs
InjectionDezocine Analgesic
InjectionTropisetron hydrochloride Antiemetic
Stability of mixtures
Glass Sodium chloride 0,9% 25°C Protect from light
Injection Dezocine 0,4 mg/ml
Injection Tropisetron hydrochloride 0,05 mg/ml
14 Day
Glass Sodium chloride 0,9% 4°C Protect from light
Injection Dezocine 0,4 mg/ml
Injection Tropisetron hydrochloride 0,05 mg/ml
14 Day
Polyolefine Sodium chloride 0,9% 25°C Protect from light
Injection Dezocine 0,4 mg/ml
Injection Tropisetron hydrochloride 0,05 mg/ml
14 Day
Polyolefine Sodium chloride 0,9% 4°C Protect from light
Injection Dezocine 0,4 mg/ml
Injection Tropisetron hydrochloride 0,05 mg/ml
14 Day

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