Last update :
02/12/2020
References   References 4430  
Type : Journal
Web link : http://dx.doi.org/10.1097/MD.0000000000007979

Research teams : Hubei - Dongfeng Hospital, Hubei University of Medicine
Authors : Fang B-X, Wang L-H, Liu H-M, Chen F-C, Liu J.
Title : Stability study of dezocine in 0.9% sodium chloride solutions for patient-controlled analgesia administration.
Reference : Medicine 96:35(e7979) 2017

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed

List of drugs
InjectionDezocine Analgesic
Stability in solutions Glass Sodium chloride 0,9% 0,3 >> 0,6 mg/ml 25°C Protect from light
72 Hour
Stability in solutions Glass Sodium chloride 0,9% 0,3 >> 0,6 mg/ml 4°C Protect from light
14 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0,3 >> 0,6 mg/ml 25°C Protect from light
72 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 0,3 >> 0,6 mg/ml 4°C Protect from light
14 Day

  Mentions Légales