Last update :
02/12/2020
References   References 4408  
Type : Journal

Research teams : Juiz de Fora - Ortofarma - Quality Control Laboratories
Authors : Polonini H, Loures da Silva S, Neves Cunha C, de Oliveira Ferreira A, Anagnostou K, Dijkers E.
Title : Stability of Azathioprine, Clonidine Hydrochloride, Clopidogrel Bisulfate, Ethambutol Hydrochloride, Griseofulvin, Hydralazine Hydrochloride, Nitrofurantoin, and Thioguanine Oral Suspensions Compounded with SyrSpend SF PH4.
Reference : Int J Pharm Compound ;24,3:252-262 2020

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionAzathioprine Immunosuppressant
Stability in solutions Plastic bottle Powder 7500 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
14 Day
Stability in solutions Plastic bottle Powder 7500 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
14 Day
Stability in solutions Plastic bottle Tablets 7500 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
7 Day
Oral solutionClonidine hydrochloride Antihypertensive
Stability in solutions Plastic bottle Powder 15 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
Stability in solutions Plastic bottle Powder 15 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
90 Day
Oral solutionClopidogrel bisulfate Various
Factors which affect stability Temperature > 25°C Induces Degradation
Stability in solutions Plastic bottle Tablets 750 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
Oral solutionEthambutol hydrochloride Antibiotic
Stability in solutions Plastic bottle Tablets 7500 mg
Combutol®
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
30 Day
Stability in solutions Plastic bottle Powder 7500 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
Stability in solutions Plastic bottle Powder 15 000 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
Stability in solutions Plastic bottle Tablets 7500 mg
Combutol®
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
30 Day
Stability in solutions Plastic bottle Powder 7500 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
90 Day
Stability in solutions Plastic bottle Powder 15 000 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
90 Day
Oral solutionGriseofulvine Antifungal
Stability in solutions Plastic bottle Powder 3750 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
Stability in solutions Plastic bottle Powder 3750 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
90 Day
Oral solutionHydralazine hydrochloride Antihypertensive
Stability in solutions Plastic bottle Powder 600 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
Stability in solutions Plastic bottle Powder 600 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
90 Day
Oral solutionNitrofurantoin Antibiotic
Stability in solutions Plastic bottle Powder 1500 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
Stability in solutions Plastic bottle Powder 1500 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
90 Day
Oral solutionThioguanine Anticancer drug
Stability in solutions Plastic bottle Tablets 375 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
Stability in solutions Plastic bottle Tablets 375 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
90 Day

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