Last update :
27/09/2020
References   References 4406  
Type : Journal

Research teams : Montreal - Centre hospitalier Sainte Justine
Authors : Friciu M, Alarie H, Beauchemin M, Forest JM, Leclair G.
Title : Stability of Methadone Hydrochloride for Injection in Saline Solution
Reference : Can J Hosp Pharm 2020;73(2):141-4 2020

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 

List of drugs
InjectionMethadone hydrochloride Analgesic
Stability in solutions Glass Sodium chloride 0,9% 5 mg/ml 23-27°C Not specified
180 Day
Stability in solutions Glass Sodium chloride 0,9% 5 mg/ml 5°C Not specified
180 Day

  Mentions Légales