Last update :
13/08/2020
References   References 4373  
Type : Journal

Research teams : Lille - Faculté des Sciences Pharmaceutiques et Biologiques
Authors : Masse M, Genay S, Martin Mena A, Carta N, Lannoy D, Barthélémy C, Décaudin B, Odou P.
Title : Evaluation of the stability of vancomycin solutions at concentrations used in clinical services.
Reference : EJHP 2020

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 

List of drugs
InjectionVancomycin hydrochloride Antibiotic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 25 mg/ml 23-27°C Light
24 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 40 mg/ml 23-27°C Light
24 Hour

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