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References   References 4353  
Type : Journal
Web link : https://doi.org/10.1111/jcpt.13008
Research teams : Hobart - University of Tasmania, School of Pharmacy
Authors : Lu D, Harmanjeet H, Wanandy T, Paine M, . PetersonG.M, Patel R.
Title : Physicochemical stability of extemporaneously prepared clonidine solutions for use in neonatal abstinence syndrome.
Reference : J Clin Pharm Ther 2019
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
Oral solutionClonidine hydrochloride Antihypertensive
Stability in solutions Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
Dextrose 5% >> 30 mL
35°C Protect from light
24 Hour
Stability in solutions Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
Dextrose 5% >> 30 mL
35°C Protect from light
24 Hour
Stability in solutions Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
Dextrose 10 % >> 30 mL
35°C Protect from light
24 Hour
Stability in solutions Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
Dextrose 10 % >> 30 mL
35°C Protect from light
24 Hour
Stability in solutions Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
NaCl 0.9% >> 30 mL
35°C Protect from light
24 Hour
Stability in solutions Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
NaCl 0.9% >> 30 mL
35°C Protect from light
24 Hour
Stability in solutions Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
Dextrose 10 % >> 30 mL
4°C Protect from light
7 Day
Stability in solutions Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
Dextrose 5% >> 30 mL
4°C Protect from light
7 Day
Stability in solutions Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
Dextrose 5% >> 30 mL
4°C Protect from light
7 Day
Stability in solutions Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
Dextrose 10 % >> 30 mL
4°C Protect from light
7 Day
Stability in solutions Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
NaCl 0.9% >> 30 mL
4°C Protect from light
7 Day
Stability in solutions Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
NaCl 0.9% >> 30 mL
4°C Protect from light
7 Day
  Mentions Légales