Last update :
28/04/2024
InfoStab
Infostab
List of drugs
List of drugs
Summary lists
Summary lists
Search for compatibilities
Search for compatibilities
Y-site compatibility table
Y-site compatibility table
References
References
Research teams
Research teams
Valistab
Valistab
Poster
Poster
Links
Links
Sponsors
Sponsors
Authors
Authors
User’s guide
User’s guide
Newsletter
Newsletter
References   References 4245  
Type : Poster
Icone.pdf
1337Ko
Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Iazetta J, Law S, Adhikari NKJ, Lamontagne F, Kanji S, Walker SE.
Title : Physical Compatibility and Stability of Ascorbic acid Injection in Polyvinyl Chloride Minibags at 4ºC and Room Temperature (25ºC).
Reference : 2019
Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
No visual inspection
List of drugs
InjectionAscorbic acid Vitamin
Factors which affect stability Temperature 25°C Induces Reduced stability
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 36,6 >> 91,4 mg/ml 25°C Protect from light
10 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 36,6 >> 91,4 mg/ml 4°C Protect from light
14 Day
  Mentions Légales