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References   References 4185  
Type : Journal
Web link : https://doi.org/10.1177/0018578718802586
Research teams : Rochester - Wegmans School of Pharmacy
Authors : Sabins D, Diep T, McCartan P, Patel S, Zhao F
Title : Stability and Compatibility of Diphenhydramine Hydrochloride in Intravenous Admixtures : A New Look at an Old Drug.
Reference : Hosp Pharm ; 54, 5: 330-334. 2019
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,2 mg/ml 2-8°C Not specified
14 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 2-8°C Not specified
14 Day
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