Last update :
03/05/2024
References   References 41  
Type : Journal

Research teams : New Orleans - College of Pharmacy, Xavier University of Louisiana
Authors : Pramar YV, Loucas VA, El-Rachidi A.
Title : Stability of midazolam hydrochloride in syringes and IV fluids.
Reference : Am J Health-Syst Pharm ; 54: 913-915. 1997

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionMidazolam hydrochloride Anxiolytic
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,5 mg/ml 24-26°C Protect from light
36 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,5 mg/ml 39-41°C Protect from light
36 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,5 mg/ml 4-6°C Protect from light
36 Day
Stability in solutions Polypropylen Syringe None 5 mg/ml 24-26°C Protect from light
36 Day

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