Last update :
18/04/2024
References   References 4089  
Type : Journal

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Godet M, Simar J, Closset M, Hecq J.D, Braibant M, Soumoy L, Gillet P, Jamart J, Bihin B, Galanti L.
Title : Stability of Concentrated Solution of Vancomycin Hydrochloride in Syringes for Intensive Care Units.
Reference : Pharmaceutical Technology in Hospital Pharmacy ;3,1:23-30 2018

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Microscopic examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionVancomycin hydrochloride Antibiotic
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 41.67 mg/ml 18-25°C Light
48 Hour

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