Last update :
28/04/2024
References   References 4067  
Type : Journal

Research teams : Heidelberg - Medizinische Universitätklinik
Authors : Pinder N, Pelzl L.H; Walther G, Backhaus J, Kurzai O, Hoppe-Ticky T.
Title : Caspofungin infusion solutions (50 mg/mL): chemical stability and antifungal activity against Candida spp.
Reference : Pharmazie ;72:197-199 2017

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Method not shown but the article refers to a validated method
No visual inspection
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
No comments for the degradation products

List of drugs
InjectionCaspofungin acetate Antifungal
Stability in solutions Polypropylene Sodium chloride 0,9% 0.5 mg/ml 2-8°C Not specified
28 Day

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