Last update :
10/08/2022
References   References 4059  
Type : Journal
Web link : https://ejhp.bmj.com/content/25/e2/e115

Research teams : Hobart - University of Tasmania, School of Pharmacy
Authors : Madfai F, Zaidi S, Ming L, Wanandy T, Patel R.
Title : Physical and chemical stability of ceftaroline in an elastomeric infusion device.
Reference : EJHP ; 25, e2 2017

Level of Evidence : 
Level of evidence C+
Physical stability : 
Visual examination Turbidimetry Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionCeftaroline fosamil Antibiotic
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 6 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 6 mg/ml 30°C Protect from light
12 Hour
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 6 mg/ml 35°C Protect from light
12 Hour
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 6 mg/ml 4°C Protect from light
6 Day
Stability in solutions Polyisoprene elastomer Glucose 5% 6 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Polyisoprene elastomer Glucose 5% 6 mg/ml 30°C Protect from light
12 Hour
Stability in solutions Polyisoprene elastomer Glucose 5% 6 mg/ml 35°C Protect from light
6 Hour
Stability in solutions Polyisoprene elastomer Glucose 5% 6 mg/ml 4°C Protect from light
6 Day

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