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References   References 4024  
Type : Poster
Research teams : Paris - University Hospital Pitié-Salpétrière,Department of pharmacy
Authors : Sadou Yaye H, Rieber Z, HassaniI L, Hoffmann-Martinot C, Babiard M, Aouti H, Bellanger A, Tilleul P.
Title : Pénurie mondiale d'Etopophos et conséquences pratiques : Intérêt des études de stabilité dans le choix d'un générique.
Reference : SFPO Congress 2017 - Nantes 2017
Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products detected but not quantified
Unencrypted results (eg graphic)
Method not shown but the article refers to a validated method
List of drugs
InjectionEtoposide Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 0,4 mg/ml 25°C Light
21 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0,6 mg/ml 25°C Light
21 Day
Stability in solutions Polyolefine Glucose 5% 0,4 mg/ml 25°C Light
21 Day
Stability in solutions Polyolefine Glucose 5% 0,6 mg/ml 25°C Light
21 Day
  Mentions Légales