Last update :
28/11/2020
References   References 3993  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=4322

Research teams : Aurora - Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado
Authors : McHenry A.R,Wempe M.F., Rice P.J.
Title : Stability of Extemporaneously Prepared Hydroxychloroquine Sulfate 25-mg/mL Suspensions in Plastic Bottles and Syringes.
Reference : Int J Pharm Compound ; 3: 251-254 2017

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
Oral solutionHydroxychloroquine sulfate Anti-inflammatory
Stability in solutions Plastic bottle Tablets 750 mg
? (Mylan Company)
Oral Mix® >> 30 ml
19-23°C Protect from light
112 Day
Stability in solutions Plastic bottle Tablets 750 mg
? (Mylan Company)
Oral Mix SF® >> 30 ml
19-23°C Protect from light
112 Day
Stability in solutions Plastic bottle Tablets 750 mg
? (Mylan Company)
Oral Mix® >> 30 ml
4°C Protect from light
112 Day
Stability in solutions Plastic bottle Tablets 750 mg
? (Mylan Company)
Oral Mix SF® >> 30 ml
4°C Protect from light
112 Day
Stability in solutions Syringe Tablets 37.5 mg
? (Mylan Company)
Oral Mix® >> 1.5 ml
19-23°C Protect from light
112 Day
Stability in solutions Syringe Tablets 37.5 mg
? (Mylan Company)
Oral Mix SF® >> 1.5 ml
19-23°C Protect from light
112 Day
Stability in solutions Syringe Tablets 37.5 mg
? (Mylan Company)
Oral Mix® >> 1.5 ml
4°C Protect from light
112 Day
Stability in solutions Syringe Tablets 37.5 mg
? (Mylan Company)
Oral Mix SF® >> 1.5 ml
4°C Protect from light
112 Day

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