Last update :
03/05/2024
References   References 388  
Type : Journal

Research teams : Chicago - University of Illinois, College of Pharmacy
Authors : Raineri DL, Cwik MJ, Rodvold KA, Deyo KL, Scaros LP, Fischer JH.
Title : Stability of nizatidine in commonly used intravenous fluids and containers.
Reference : Am J Hosp Pharm ; 45: 1523-1529. 1988

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionNizatidine Antihistamine (H2)
Stability in solutions Glass Water for Injection 0,75 & 1,5 & 3 mg/ml 25°C Light
7 Day
Stability in solutions Glass Water for Injection 0,75 & 1,5 & 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,75 & 1,5 & 3 mg/ml 25°C Light
7 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,75 & 1,5 & 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass Ringer’s lactate solution 0,75 & 1,5 & 3 mg/ml 25°C Light
7 Day
Stability in solutions Glass Ringer’s lactate solution 0,75 & 1,5 & 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass Glucose 10% 0,75 & 1,5 & 3 mg/ml 25°C Light
7 Day
Stability in solutions Glass Glucose 10% 0,75 & 1,5 & 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride Water for Injection 0,75 & 3 mg/ml -20°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride Water for Injection 0,75 & 3 mg/ml 25°C Light
7 Day
Stability in solutions Polyvinyl chloride Water for Injection 0,75 & 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,75 & 3 mg/ml -20°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,75 & 3 mg/ml 25°C Light
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,75 & 3 mg/ml 4°C Protect from light
7 Day

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