Last update :
22/01/2021
References   References 3874  
Type : Journal
Web link : http://www.em-consulte.com/article/1066136/article/long-term-stability-of-ketamine-hydrochloride-50mg

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Huvelle S, Godet M, Hecq J.D, Gillet P, Bihin B, Jamart J, Galanti L.
Title : Long-term stability of ketamine hydrochloride 50 mg/ml injection in 3 ml syringes
Reference : Ann Pharm Fr ; 74: 283-287. 2016

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination Turbidimetry Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values

List of drugs
InjectionKetamine hydrochloride General anesthetic
Stability in solutions Polypropylen Syringe None 50 mg/ml 25°C Protect from light
180 Day

  Mentions Légales