Last update :
03/05/2024
References   References 3850  
Type : Journal
Web link : http://www.ejcancer.com/article/S0959-8049%2816%2900046-0/abstract

Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : Bardo-Brouard P, Vieillard V, Shekarian T, Marabelle A, Astier A, Paul M.
Title : Stability of ipilimumab in its original vial after opening allows its use for at least 4 weeks and facilitates pooling of residues.
Reference : Eur J Cancer ; 58: 8-16. 2016

Level of Evidence : 
Level of evidence A+
Physical stability : 
Turbidimetry Protein: Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: ionic chromatography
Protein: ultraviolet spectrometry and second derivative
Other methods : 
Comments : 
Proteins: biological activity by enzymatic technique

List of drugs
InjectionIpilimumab Anticancer drug
Stability in solutions Partially used vials None 5 mg/ml 25°C Protect from light
28 Day
Stability in solutions Partially used vials None 5 mg/ml 4°C Protect from light
28 Day

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