Last update :
28/04/2024
References   References 3818  
Type : Journal
Web link : https://www.degruyter.com/view/j/pthp.2017.2.issue-1/pthp-2016-0023/pthp-2016-0023.xml?format=INT

Research teams : Paris - University Hospital Hôtel Dieu, Paris
Authors : Balouzet C, Chanat C, Jobard M, Brandely-Piat M-L, Chast F.
Title : Stability of 25 mg/mL 5-azacitidine suspension kept in fridge after freezing.
Reference : Pharmaceutical Technology in Hospital Pharmacy ;2, 1:11-16. 2017

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination Microscopic examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Degradation products identified

List of drugs
InjectionAzacitidine Anticancer drug
Stability in solutions Polypropylen Syringe Water for Injection (4°C) 25 mg/ml -20°C Protect from light
30 Day
Stability in solutions Polypropylen Syringe Water for Injection (4°C) 25 mg/ml 2-8°C Protect from light
3 Day
Conflicting data

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