Last update :
28/04/2024
References   References 370  
Type : Journal

Research teams : Albuquerque - University of New Mexico Health Sciences Center, College of Pharmacy
Authors : Raymond GG, Reed MT, Teagarden JR, Story K, Geberbauer CW.
Title : Stability of procainamide hydrochloride in neutralized 5% dextrose injection.
Reference : Am J Hosp Pharm ; 45: 2513-2517. 1988

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
No visual inspection

List of drugs
InjectionProcainamide hydrochloride Anti-arrhythmic
Factors which affect stability Temperature Increase Induces Degradation
Factors which affect stability Concentration Reduction Induces Degradation
Stability in solutions Polyvinyl chloride Glucose 5% 4 mg/ml 5°C Protect from light
6 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 4 & 8 mg/ml 23-25°C Not specified
6 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 8 mg/ml 5°C Protect from light
24 Hour

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