Last update :
28/04/2024
References   References 3538  
Type : Journal
Web link : http://www.krankenhauspharmazie.de/archiv/verzeichnis/2013/11.html

Research teams : Mainz - University Medical Center, Johannes Gutenberg
Authors : Gilcher Th, Heeb R M, Krämer I.
Title : Physikalisch-chemische Stabilität einer Metoprolol-Injektionslösung 1 mg/ml, 50 ml.
Reference : Krankenhauspharmazie ; 11: 524-525. 2013

Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
No comments for the degradation products
Stability indicating capability inadequately assessed
No visual inspection

List of drugs
InjectionMetoprolol tartrate Anti-arrhythmic
Stability in solutions Glass Sodium chloride 0,9% 1 mg/ml 25°C Protect from light
230 Day

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