Last update :
18/04/2024
References   References 3418  
Type : Journal
Web link : http://www.ijpbsonline.com/issue-1-2013.html

Research teams : Sevilla - University Hospital “Virgen del Rocío, Department of Pharmacy
Authors : Berruezo garcia J, Espinosa Bosch M, Sanchez Rojas F, Bosch Ojeda C
Title : Chemical stability of bortezomib solutions in original manufacturer vial at room temperature and in syringe at 4°C.
Reference : Int J Pharm Bio Sci ; 3, 1: 449-458. 2013

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
No comments for the degradation products

List of drugs
InjectionBortezomib Anticancer drug
Stability in solutions Glass Sodium chloride 0,9% 2,5 mg/ml 25°C Protect from light
33 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2,5 mg/ml 4°C Protect from light
23 Day

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