Last update :
09/04/2024
References   References 3378  
Type : Journal
Web link : http://www.ajhp.org/content/70/6/515.abstract

Research teams : Wuhan - Wuhan University, College of Pharmacy
Authors : Chen F-C, Fang B-X, Li P, Yang J-G, Zhou B-H.
Title : Compatibility of butorphanol and droperidol in 0.9% sodium chloride injection
Reference : Am J Health-Syst Pharm ; 70:515-519. 2013

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionButorphanol tartrate Analgesic
Compatible 0,08 mg/ml + InjectionDroperidol 0,05 mg/ml + Sodium chloride 0,9%
InjectionDroperidol Neuroleptic
Compatible 0,05 mg/ml + InjectionButorphanol tartrate 0,08 mg/ml + Sodium chloride 0,9%
Stability of mixtures
Glass Sodium chloride 0,9% 25°C Protect from light
Injection Butorphanol tartrate 0.08 mg/ml
Injection Droperidol 0.05 mg/ml
15 Day
Glass Sodium chloride 0,9% 4°C Protect from light
Injection Droperidol 0.05 mg/ml
Injection Butorphanol tartrate 0.08 mg/ml
15 Day
Polyvinyl chloride Sodium chloride 0,9% 25°C Protect from light
Injection Butorphanol tartrate 0.08 mg/ml
Injection Droperidol 0.05 mg/ml
15 Day
Polyvinyl chloride Sodium chloride 0,9% 4°C Protect from light
Injection Droperidol 0.05 mg/ml
Injection Butorphanol tartrate 0.08 mg/ml
15 Day

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