Last update :
28/04/2024
References   References 3342  
Type : Journal
Icone.pdf
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Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Vigneron J, D'Huart E, Demoré B.
Title : Stability of Bendamustine Solutions: Influence of Sodium Chloride Concentration, Temperature and Container.
Reference : Pharmaceutical Technology in Hospital Pharmacy ;3,1:13-21 2018

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
No comments for the degradation products
Method not shown but the article refers to a validated method

List of drugs
InjectionBendamustine hydrochloride Anticancer drug
Stability in solutions Glass Water for Injection 2.5 mg/ml 4°C Protect from light
8 Hour

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