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References   References 3308  
Type : Journal
Web link : http://aac.asm.org/content/56/6/3435.abstract
Research teams : Parkville - Monash University, Victorian College of Pharmacy
Authors : Neoh C.F, Jacob J, Leung L, Li J, Stathopoulos A, Stewart K, Kong D.C.M.
Title : Stability of Extemporaneously Prepared 0.5-Percent Caspofungin Eye Drops: a Potential Cost-Savings Exercise.
Reference : Antimicrob Agents Chemother ; 56: 3435-3437; 2012
Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Measurement of osmolality PH measurement 
Comments : 
List of drugs
Eye-dropsCaspofungin acetate Antifungal
Factors which affect stability Temperature Increase Induces Degradation
Stability in solutions Plastic bottle Medicine bottle for injection 50 mg
cancidas®
Water for injection 10,5 ml
25°C Not specified
3 Day
Stability in solutions Plastic bottle Medicine bottle for injection 50 mg
cancidas®
Water for injection 10,5 ml
3-5°C Not specified
28 Day
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