Last update :
18/04/2024
References   References 3126  
Type : Journal
Web link : https://www.sciencedirect.com/science/article/pii/S0885392410002605

Research teams : Villejuif - Institut Gustave Roussy, Department of Pharmacy
Authors : Amri A, Achour AB, Chachaty E, Mercier L, Bourget P, Paci A.
Title : Microbiological and Physicochemical Stability of Oxycodone Hydrochloride Solutions for Patient-Controlled Delivery Systems.
Reference : J Pain Symptom Manage ; 40, 1: 87-94. 2010

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
Stability indicating capability inadequately assessed

List of drugs
InjectionOxycodone hydrochloride Analgesic
Stability in solutions Polyvinyl chloride Water for Injection 1 mg/ml 15-25°C With or without light
28 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 15-25°C With or without light
28 Day
Stability in solutions Polyvinyl chloride None 10 mg/ml 15-25°C With or without light
28 Day

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