| Type : |
Journal |
|
| Forskerteamet : |
Rochester - University of Rochester Medical Center, Department of Pharmacy |
| Forfattere : |
Dentinger PJ, Swenson CF, Anaizi NH. |
| Tittel : |
Stability of amphotericin B in an extemporaneously compounded oral suspension. |
| Nummer : |
Am J Health-Syst Pharm ; 58: 1021-1024. 2001 |
|
| Nivå of Evidence : |
|
| fysisk stabilitet : |
|
| kjemisk stabilitet : |
|
| andre metoder : |
|
| Kommentarer : |
|
Lister
Amphotericin B
|
 |
 |
 |
 |
30 g Amphotericin B |
| Na2HPO4 |
4.77 g |
| NaH2PO4 |
2.88 g |
| Natriumbenzoat |
300 mg |
| Natriummetabisulfitt |
450 mg |
| Sitronsyre |
2.25 g |
| Karboksymetylcellulose |
1% 37.5 ml |
| Metylparaben |
300 mg |
| Propylparaben |
60 mg |
| Kirsebærsmak |
1.2 ml |
| Propylenglykol |
3 ml |
| Sitronsyre |
>> pH 4.3 |
| Renset vann |
>> 300 ml |
|
22-25°C |
 |
| 93 |
 |
|
|
|
|