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References   References 283  
Type : Journal
Research teams : Memphis - Regional Medical center of Memphis, Department of Pharmacy
Authors : Lee MD, Hess MM, Boucher BA, Apple AM.
Title : Stability of amphotericin B in 5% dextrose injection stored at 4 or 25°C for 120 hours.
Reference : Am J Hosp Pharm ; 51: 394-396. 1994
Level of Evidence : 
Level of evidence C+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
List of drugs
InjectionAmphotericin B Antifungal
Stability in solutions Polyvinyl chloride Glucose 5% 0,2 & 0,5 mg/ml 25°C Light
120 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 0,2 & 0,5 & 1 mg/ml 4°C Protect from light
120 Hour
  Mentions Légales