Last update :
18/04/2024
References   References 2825  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=3996

Research teams : Bâle - F.Hoffman La Roche Ltd
Authors : Mueller C, Dietel E, Heynen S, Nalenz H, Goldbach P, Mahler H, Schmidt J, Grauschopf U, Schoenhammer K.
Title : Physico-chemical Stability of MabThera Drug-product Solution for Subcutaneous Injection under In-use Conditions with Different Administration Materials.
Reference : Int J Pharm Compound ; 19, 3: 261-267. 2015

Level of Evidence : 
Level of evidence A+
Physical stability : 
Turbidimetry Protein: Size Exclusion Chromatography 
Chemical stability : 
Protein: ionic chromatography
Protein: ultraviolet spectrometry
Other methods : 
Comments : 
Proteins: biological activity by cell culture

List of drugs
InjectionRituximab Anticancer drug
Stability in solutions Polypropylen Syringe None 120 mg/ml 2-8°C Not specified
28 Day
Stability in solutions Polypropylen Syringe None 120 mg/ml 30°C Light
24 Hour

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