Last update :
09/04/2024
References   References 2814  
Type : Journal

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Lebitasy M, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L.
Title : Long-term stability of tramadol hydrochloride and droperidol mixture in 5% dextrose infusion polyolefin bags at 5 +/- 3°C.
Reference : Ann Pharm Fr ; 67: 272-277. 2009

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionDroperidol Neuroleptic
Compatible 0,025 mg/ml + InjectionTramadol hydrochloride 1 mg/ml + Glucose 5%
InjectionTramadol hydrochloride Analgesic
Compatible 1 mg/ml + InjectionDroperidol 0,025 mg/ml + Glucose 5%
Stability of mixtures
Polyethylene Glucose 5% 2-8°C Protect from light
Injection Tramadol hydrochloride 1 mg/ml
Injection Droperidol 0,025 mg/ml
32 Day

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