Last update :
05/12/2025
References   References 2682  
Type : Journal
Web link : https://doi.org/10.1111/j.2042-7174.1991.tb00520.x

Research teams : London - Moorfields Eye Hospital,NIHR Biomedical Research Centre
Authors : Oldham GB.
Title : Formulation and stability of cefuroxime eye-drops.
Reference : Int J Pharm Pract ; 1: 19-22. 1991

Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 

List of drugs
Eye-dropsCefuroxime sodium Antibiotic
Factors which affect stability Temperature Increase Induces Reduced stability
Stability in solutions Glass Medicine bottle for injection 550 mg
Zinacef®
Water for injection >> 10 ml
-30°C Protect from light
365 Day
Stability in solutions Glass Medicine bottle for injection 550 mg
Zinacef®
Water for injection >> 10 ml
25°C Protect from light
24 Hour
Stability in solutions Glass Medicine bottle for injection 550 mg
Zinacef®
Water for injection >> 10 ml
2°C Protect from light
28 Day
Stability in solutions plastic bottle Medicine bottle for injection 550 mg
Zinacef®
Water for injection >> 10 ml
25°C Protect from light
24 Hour
Stability in solutions plastic bottle Medicine bottle for injection 550 mg
Zinacef®
Water for injection >> 10 ml
2°C Protect from light
21 Day

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