Last update :
06/05/2024
References   References 2538  
Type : Journal
Web link : https://doi.org/10.1177/106002809502901005

Research teams : Dunedin - University of Otago
Authors : Fawcett JP, Boulton DW, Jiang R, Woods DJ.
Title : Stability of hydrocortisone oral suspensions prepared from tablets and powder.
Reference : Ann Pharmacotherapy ;29:987-990. 1995

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionHydrocortisone Anti-inflammatory
Stability in solutions Plastic bottle Tablets 250 mg
®=? (Douglas)
Polysorbate 80 0.5 ml
Sodium carboxymethylcellulose 1000 mg
Simple syrup 10 ml
Methylparaben 20 mg
Propylparaben 80 mg
Citric acid 600 mg
Purified water >> 100 ml
25°C Protect from light
91 Day
Stability in solutions Plastic bottle Tablets 250 mg
®=? (Douglas)
Polysorbate 80 0.5 ml
Sodium carboxymethylcellulose 1000 mg
Simple syrup 10 ml
Methylparaben 20 mg
Propylparaben 80 mg
Citric acid 600 mg
Purified water >> 100 ml
40°C Protect from light
31 Day
Stability in solutions Plastic bottle Powder 250 mg
Hydrocortisone
Polysorbate 80 0.5 ml
Sodium carboxymethylcellulose 1000 mg
Simple syrup 10 ml
Methylparaben 20 mg
Propylparaben 80 mg
Citric acid 600 mg
Purified water >> 100 ml
40°C Protect from light
91 Day
Stability in solutions Plastic bottle Tablets 250 mg
®=? (Douglas)
Polysorbate 80 0.5 ml
Sodium carboxymethylcellulose 1000 mg
Simple syrup 10 ml
Methylparaben 20 mg
Propylparaben 80 mg
Citric acid 600 mg
Purified water >> 100 ml
5°C Protect from light
91 Day

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