Last update :
06/05/2024
References   References 2367  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=2263

Research teams : Houston - University of Houston, College of Pharmacy
Authors : Gupta V.D.
Title : Chemical stability of hydralazine hydrochloride after reconstitution in 0.9% sodium chloride injection or 5% dextrose injection for infusion.
Reference : Int J Pharm Compound ; 9, 5: 399-401. 2005

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionHydralazine hydrochloride Antihypertensive
Factors which affect stability Solvent Glucose 5% Induces Degradation
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,2 mg/ml 25°C Not specified
1 Day
Incompatible + Glucose 5%

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