Last update :
03/05/2024
References   References 231  
Type : Journal

Research teams : Travis AFB - David Grant Medical Center, Travis Air Force bas
Authors : Hagan RL, Jacobs III LF, Pimsler M, Merritt GJ.
Title : Stability of midazolam hydrochloride in 5% dextrose injection or 0.9% sodium chloride injection over 30 days.
Reference : Am J Hosp Pharm ; 50: 2379-2381. 1993

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionMidazolam hydrochloride Anxiolytic
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,5 mg/ml 2-6°C Protect from light
30 Day
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,5 mg/ml 22°C-24°C Protect from light
30 Day

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