Last update :
28/04/2024
References   References 2267  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/65/7/636

Research teams : Ann Arbor - University of Michigan, College of Pharmacy
Authors : Kraft MD, Johnson CE, Chung C, Julian F.
Title : Stability of metoprolol tartrate injection 1 mg/ml undiluted and 0.5 mg/ml in 0.9% sodium chloride injection and 5% dextrose injection.
Reference : Am J Health-Syst Pharm ; 65, 7: 636-638. 2008

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionMetoprolol tartrate Anti-arrhythmic
Stability in solutions Not specified NaCl 0,9% or Glucose 5% 0.5 mg/ml 23-25°C Not specified
30 Hour
Stability in solutions Not specified None 1 mg/ml 23-25°C Not specified
30 Hour

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